Paul Mahon, Ph.D.

Professor of Biology


Degrees Earned

B.A., Assumption College; Natural Sciences, 1966
Ph.D., Clark University; Biology/Biochemistry, 1973
Ph.D. Thesis Title: “On the Role of Acetylcholinesterase in the Mechanism of Action of Pentylenetetrazol on the Nervous System”

Undergraduate Courses Taught

Biology and Chemistry of Nutrition
Genetics

Publications & Editorships

Wang Z hiyu, Mirza A.M ., Li J ., Mahon P.J ., Iorio R.M . “An oligosaccharide at the C-terminus of the F-specific domain in the stalk of the human parainfluenza virus 3 hemagglutinin-neuraminidase modulates fusion.” Virus Res. 99(2) (2004):177-85

Iorio R.M., Field G.M., Sauvron J.M., Mirza A.M., Deng R., Mahon P.J., Langedijk J.P. “Structural and functional relationship between the receptor recognition and neuraminidase activities of the Newcastle disease virus hemagglutinin-neuraminidase protein: receptor recognition is dependent on neuraminidase activity”. J Virol. 75(4) (2001):1918-27.

Deng, Ruitang, Zhiyu Wang, Paul J. Mahon, Mark Marinello, Anne Mirza, and Ronald Iorio. “Mutations in the Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein that Interfere with Its Ability to Interact with the Homologous F Protein in the Promotion of Fusion.” Virology 253 (1999): 43-54.

Deng, R., Mirza, A.M., Mahon, P.J., and Iorio, R.M. “Functional Chimeric HN Glycoproteins Derived from Newcastle Disease Virus and Human Parainfluenza Virus-3.” Arch. Virol.13 (1997): 115-130.

Mahon, Paul, J., Ruitang Deng, Ann M. Mirza and Ronald M. Iorio. “Cooperativity in a Viral Neuraminidase and its Elimination by Antibody-selected Mutations near the Active Site.” Virology 213 (1995): 241-244.

Presentations

Mahon, Paul J., J. Li, A.M. Mirza and R.M. Iorio. “Role of Intermonomeric Hydrogen Bonds in the Structure and Function of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein” 23rd Annual Meeting of the American Society for Virology, held at McGill University, Montreal, Quebec, Canada, July 10-14, 2004.

Wang, Z., J. Li, P.J. Mahon, A.M. Mirza and R. M. Iorio. “Refinement of the F-specific domain in the human parainfluenza-3 virus HN protein” Twelfth International Conference on Negative Strand Viruses, held in Pisa, Italy, June 14-19, 2003.

Wang, Z., Deng, R., and Iorio, R.M. “Mutations in the NVD HN Protein that Modulate its Interaction with the Homologous F Protein.” 17th Annual Meeting of the American Society for Virology in Vancouver, BC, 1998.

Mahon, P.J., Deng, R., Mirza, A.M., and Iorio. R.M. “Identification of the Minimal Domain in the Paramyxovirus Hn Protein Required for the Promotion of Fusion by its Homologous F Protein.” 15th Annual Meeting of the American Society for Virology, University Of Western Ontario, London, Ontario, Canada, 1996.

Mahon, P.J., Wang, Z., Deng, R., and Iorio, R.M. “Mutations in the NVD HN Protein that Modulate its Interaction with the Homologous F Protein.” 17th Annual Meeting of the American Society for Virology in Vancouver, BC, 1998.