Jessica McCready, Ph.D.

Associate Professor of Biology

508-767-7344 Testa Science Center - Room 110

Degrees Earned

B.S., Cornell University; Nutrition; 1998
Ph.D., Virginia Commonwealth University; Anatomy, 2006
Postdoctoral Associate/TEACRS Fellow, Tufts University School of Medicine, Anatomy and Cellular Biology, 2009-2012
Postdoctoral Associate/TEACRS Fellow, Tufts University School of Medicine, Physiology, 2006 – 2009

Undergraduate Courses Taught

Mammalian Anatomy
General Physiology
Human Biology in Health and Disease
Cellular and Molecular Biology

Publications & Editorships

McCready J, Wong D, Burlison, J, Weiwen Y, Jay DG. An impermeant ganetespib analogy inhibits extracellular Hsp90-mediated cancer cell migration that involves lysyl oxidase like-2 protein. 2014 Cancers 6:1031-1046.

McCready J, Arendt LM, Glover E, Iyer V, Breindel JL, Lyle, SR, Naber, SP, Jay DG, Kuperwasser C. Adipose Stromal Cells Present during Lactation Promote Angiogenesis and Breast Tumor Growth. 2014 Breast Cancer Research. 16(1).

Arendt LM, McCready J, Keller PJ, Baker DD, Naber SP, Seewaldt V, Kuperwasser C. Obesity promotes breast cancer by CCL-2-mediated macrophage recruitment and angiogenesis. 2013 Cancer Research. 73(20):6080-6093.

Iyer V, Klebba I, McCready J, Arendt LM, Betancur-Boissel M, Wu MF, Zhang X, Lewis MT, Kuperwasser C. Estrogen promotes ER-negative tumor growth through mobilization of bone marrow-derived monocytes. 2012 Cancer Research. 72(11):2705-13.

Sims JD, McCready J, Jay DG. Extracellular Heat Shock Protein (Hsp) 70 and Hsp90a Assist in Matrix Co-Chaperones Hsp70, Hop and Hsp40 Assist in Matrix Metalloproteinase-2 Activation and Breast Cancer Cell Migration and Invasion. 2011. PLOS One. 6(4): e18848.

McCready J, Arendt LM, Rudnick JA, Kuperwasser C. The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis. 2010. Breast Cancer Research. 12(3):205

McCready J, Sims JD, Chan D, Jay DG. Secretion of extracellular hsp90a via exosomes increases cancer cell motility: a role for plasminogen activation. 2010. BMC Cancer 10(1):294

Clark AJ, Dos Santos WG, McCready J, Chen MY, Van Meter TE, Ware JL, Wolber S, Fillmore HL, Broaddus WC. Wilms’ tumor 1 expression in malignant gliomas and correlation of +KTS isoforms with p53 status. 2007. J Neurosurg. 107(3):586-592

McCready J, Sykes V, Broaddus WC, Fillmore HL. Association of a Single Nucleotide Polymorphism in the Matrix Metalloproteinase-1 Promoter with Glioblastoma. 2005. Inter J of Cancer. 117(5):781-785